Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria

m-AAA proteases exert dual functions in the mitochondrial inner membrane: they mediate the processing of specific regulatory proteins and ensure protein quality control degrading misfolded polypeptides to peptides. Loss of these activities leads to neuronal cell death in several neurodegenerative di...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bonn, Florian, Tatsuta, Takashi, Petrungaro, Carmelina, Riemer, Jan, Langer, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155303/
https://ncbi.nlm.nih.gov/pubmed/21610694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.169
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