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Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria

The vast majority of mitochondrial proteins are synthesized in the cytosol and transported into the organelle in a largely, if not completely, unfolded state. The proper function of mitochondria thus depends on folding of several hundreds of proteins in the various subcompartments of the organelle....

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Main Authors: Schreiner, Bernadette, Westerburg, Heike, Forné, Ignasi, Imhof, Axel, Neupert, Walter, Mokranjac, Dejana
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496608/
https://ncbi.nlm.nih.gov/pubmed/22993211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0420
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