OPA1 Processing Reconstituted in Yeast Depends on the Subunit Composition of the m-AAA Protease in Mitochondria

The morphology of mitochondria in mammalian cells is regulated by proteolytic cleavage of OPA1, a dynamin-like GTPase of the mitochondrial inner membrane. The mitochondrial rhomboid protease PARL, and paraplegin, a subunit of the ATP-dependent m-AAA protease, were proposed to be involved in this pro...

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Bibliografische gegevens
Hoofdauteurs: Duvezin-Caubet, Stéphane, Koppen, Mirko, Wagener, Johannes, Zick, Michael, Israel, Lars, Bernacchia, Andrea, Jagasia, Ravi, Rugarli, Elena I., Imhof, Axel, Neupert, Walter, Langer, Thomas, Reichert, Andreas S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951777/
https://ncbi.nlm.nih.gov/pubmed/17615298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0164
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