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Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol

Superoxide dismutase 1 (Sod1) is an important antioxidative enzyme that converts superoxide anions to hydrogen peroxide and water. Active Sod1 is a homodimer containing one zinc ion, one copper ion, and one disulfide bond per subunit. Maturation of Sod1 depends on its copper chaperone (Ccs1). Sod1 a...

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Autors principals: Klöppel, Christine, Suzuki, Yutaka, Kojer, Kerstin, Petrungaro, Carmelina, Longen, Sebastian, Fiedler, Sebastian, Keller, Sandro, Riemer, Jan
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192855/
https://ncbi.nlm.nih.gov/pubmed/21865594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0293
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