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Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial intermembrane space
The mitochondrial intermembrane space (IMS) harbors an oxidizing machinery that drives import and folding of small cysteine-containing proteins without targeting signals. The main component of this pathway is the oxidoreductase Mia40, which introduces disulfides into its substrates. We recently show...
Enregistré dans:
| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294668/ https://ncbi.nlm.nih.gov/pubmed/25392302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1422 |
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