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Mia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding

Many proteins of the mitochondrial IMS contain conserved cysteines that are oxidized to disulfide bonds during their import. The conserved IMS protein Mia40 is essential for the oxidation and import of these proteins. Mia40 consists of two functional elements: an N-terminal cysteine-proline-cysteine...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Peleh, Valentina, Cordat, Emmanuelle, Herrmann, Johannes M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951193/
https://ncbi.nlm.nih.gov/pubmed/27343349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16177
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