The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40

A disulphide relay system mediates the import of cysteine-containing proteins into the intermembrane space of mitochondria. This system consists of two essential proteins, Mia40 and Erv1, which bind to newly imported proteins by disulphide transfer. A third component, Hot13, was proposed to be impor...

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Bibliographische Detailangaben
Hauptverfasser: Mesecke, Nikola, Bihlmaier, Karl, Grumbt, Barbara, Longen, Sebastian, Terziyska, Nadia, Hell, Kai, Herrmann, Johannes M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Scientific Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581857/
https://ncbi.nlm.nih.gov/pubmed/18787558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.173
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