Φορτώνει......
Cooperative activation of Src family kinases by SH3 and SH2 ligands
Src family nonreceptor tyrosine kinases are kept in a repressed state by intramolecular interactions involving the SH3 and SH2 domains of the enzymes. Ligands for these domains can displace the intramolecular associations and activate the kinases. Here, we carried out in vitro activation experiments...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045694/ https://ncbi.nlm.nih.gov/pubmed/17719722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2007.07.012 |
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