Novel Adeno-Associated Virus Serotypes Efficiently Transduce Murine Photoreceptors

Severe inherited retinal diseases, such as retinitis pigmentosa and Leber congenital amaurosis, are caused by mutations in genes preferentially expressed in photoreceptors. While adeno-associated virus (AAV)-mediated gene transfer can correct retinal pigment epithelium (RPE) defects in animal models...

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Bibliografiske detaljer
Main Authors: Allocca, Mariacarmela, Mussolino, Claudio, Garcia-Hoyos, Maria, Sanges, Daniela, Iodice, Carolina, Petrillo, Marco, Vandenberghe, Luk H., Wilson, James M., Marigo, Valeria, Surace, Enrico M., Auricchio, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Gene Delivery
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045569/
https://ncbi.nlm.nih.gov/pubmed/17699581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01327-07
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