Novel Adeno-Associated Virus Serotypes Efficiently Transduce Murine Photoreceptors

Severe inherited retinal diseases, such as retinitis pigmentosa and Leber congenital amaurosis, are caused by mutations in genes preferentially expressed in photoreceptors. While adeno-associated virus (AAV)-mediated gene transfer can correct retinal pigment epithelium (RPE) defects in animal models...

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Detalhes bibliográficos
Main Authors: Allocca, Mariacarmela, Mussolino, Claudio, Garcia-Hoyos, Maria, Sanges, Daniela, Iodice, Carolina, Petrillo, Marco, Vandenberghe, Luk H., Wilson, James M., Marigo, Valeria, Surace, Enrico M., Auricchio, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045569/
https://ncbi.nlm.nih.gov/pubmed/17699581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01327-07
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