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Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa
Despite the recent success of gene-based complementation approaches for genetic recessive traits, the development of therapeutic strategies for gain-of-function mutations poses great challenges. General therapeutic principles to correct these genetic defects mostly rely on post-transcriptional gene...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085076/ https://ncbi.nlm.nih.gov/pubmed/21268285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000119 |
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