Endoribonuclease-Prepared Short Interfering RNAs Induce Effective and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication

Short interfering RNAs (siRNAs) targeting viral or cellular genes can efficiently inhibit human immunodeficiency virus type 1 (HIV-1) replication. Nevertheless, optimal HIV-1 gene silencing by siRNA requires precise complementarity with most of the target sequence. The emergence of mutations in the...

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Bibliografiset tiedot
Päätekijät: Gimenez-Barcons, Mireia, Clotet, Bonaventura, Martinez, Miguel Angel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2007
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045487/
https://ncbi.nlm.nih.gov/pubmed/17652404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00950-07
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