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Sequence Homology Required by Human Immunodeficiency Virus Type 1 To Escape from Short Interfering RNAs
Short interfering RNAs (siRNAs) targeting viral or cellular genes can efficiently inhibit human immunodeficiency virus type 1 (HIV-1) replication. Nevertheless, the emergence of mutations in the gene being targeted could lead to the rapid escape from the siRNA. Here, we simulate viral escape by syst...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346856/ https://ncbi.nlm.nih.gov/pubmed/16378959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.571-577.2006 |
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