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Poliovirus Escape from RNA Interference: Short Interfering RNA-Target Recognition and Implications for Therapeutic Approaches

Short interfering RNAs (siRNAs) directed against poliovirus and other viruses effectively inhibit viral replication. Although RNA interference (RNAi) may provide the basis for specific antiviral therapies, the limitations of RNAi antiviral strategies are ill defined. Here, we show that poliovirus re...

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Detalhes bibliográficos
Main Authors: Gitlin, Leonid, Stone, Jeffrey K., Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538575/
https://ncbi.nlm.nih.gov/pubmed/15613331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1027-1035.2005
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