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Poliovirus Escape from RNA Interference: Short Interfering RNA-Target Recognition and Implications for Therapeutic Approaches

Short interfering RNAs (siRNAs) directed against poliovirus and other viruses effectively inhibit viral replication. Although RNA interference (RNAi) may provide the basis for specific antiviral therapies, the limitations of RNAi antiviral strategies are ill defined. Here, we show that poliovirus re...

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Autors principals: Gitlin, Leonid, Stone, Jeffrey K., Andino, Raul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538575/
https://ncbi.nlm.nih.gov/pubmed/15613331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1027-1035.2005
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