Poliovirus Escape from RNA Interference: Short Interfering RNA-Target Recognition and Implications for Therapeutic Approaches

Short interfering RNAs (siRNAs) directed against poliovirus and other viruses effectively inhibit viral replication. Although RNA interference (RNAi) may provide the basis for specific antiviral therapies, the limitations of RNAi antiviral strategies are ill defined. Here, we show that poliovirus re...

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Autores principales: Gitlin, Leonid, Stone, Jeffrey K., Andino, Raul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC538575/
https://ncbi.nlm.nih.gov/pubmed/15613331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1027-1035.2005
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