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Preexisting Immunity to Poliovirus Does Not Impair the Efficacy of Recombinant Poliovirus Vaccine Vectors

Recombinant viruses are attractive candidates for the development of novel vaccines. A number of viruses have been engineered as vaccine vectors to express antigens from other pathogens or tumors. Inoculation of susceptible animals with this type of recombinant virus results in the induction of both...

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Autors principals: Mandl, Stefanie, Hix, Laura, Andino, Raul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC113958/
https://ncbi.nlm.nih.gov/pubmed/11134275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.622-627.2001
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