Construction, Safety, and Immunogenicity in Nonhuman Primates of a Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine

We previously reported construction of a chimeric yellow fever-dengue type 2 virus (YF/DEN2) and determined its safety and protective efficacy in rhesus monkeys (F. Guirakhoo et al., J. Virol. 74:5477–5485, 2000). In this paper, we describe construction of three additional YF/DEN chimeras using prem...

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Bibliographic Details
Main Authors: Guirakhoo, F., Arroyo, J., Pugachev, K. V., Miller, C., Zhang, Z.-X., Weltzin, R., Georgakopoulos, K., Catalan, J., Ocran, S., Soike, K., Ratterree, M., Monath, T. P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114964/
https://ncbi.nlm.nih.gov/pubmed/11462001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7290-7304.2001
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