Targets of Small Interfering RNA Restriction during Human Immunodeficiency Virus Type 1 Replication

Small interfering RNAs (siRNAs) have been shown to effectively inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro. The mechanism(s) for this inhibition is poorly understood, as siRNAs may interact with multiple HIV-1 RNA species during different steps of the retroviral life cyc...

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Autores principales: Gao, Yong, Lobritz, Michael A., Roth, Justin, Abreha, Measho, Nelson, Kenneth N., Nankya, Immaculate, Moore-Dudley, Dawn M., Abraha, Awet, Gerson, Stanton L., Arts, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259002/
https://ncbi.nlm.nih.gov/pubmed/18199654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02126-07
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