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Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

The stress-activated protein kinase (SAPK, alternatively JNK) is activated rapidly by cell stress stimuli such as inflammatory cytokines and oxidative stress, and more slowly by the initiation of the apoptotic cell death response by events such as ligation of the Fas protein. Mitogen-activated prote...

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Autori principali: Deak, Joseph C., Cross, Janet V., Lewis, Margaret, Qian, Yongyi, Parrott, Louis A., Distelhorst, Clark W., Templeton, Dennis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20423/
https://ncbi.nlm.nih.gov/pubmed/9576928
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