The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase

BACKGROUND: Dietary isothiocyanates (ITCs) are electrophilic compounds that have diverse biological activities including induction of apoptosis and effects on cell cycle. They protect against experimental carcinogenesis in animals, an activity believed to result from the transcriptional induction of...

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Main Authors: Cross, Janet V, Foss, Frank W, Rady, Joshua M, Macdonald, Timothy L, Templeton, Dennis J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central|1 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071920/
https://ncbi.nlm.nih.gov/pubmed/17894894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-183
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