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The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase

BACKGROUND: Dietary isothiocyanates (ITCs) are electrophilic compounds that have diverse biological activities including induction of apoptosis and effects on cell cycle. They protect against experimental carcinogenesis in animals, an activity believed to result from the transcriptional induction of...

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Detalhes bibliográficos
Main Authors: Cross, Janet V, Foss, Frank W, Rady, Joshua M, Macdonald, Timothy L, Templeton, Dennis J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central|1 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071920/
https://ncbi.nlm.nih.gov/pubmed/17894894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-183
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