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The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase

BACKGROUND: Dietary isothiocyanates (ITCs) are electrophilic compounds that have diverse biological activities including induction of apoptosis and effects on cell cycle. They protect against experimental carcinogenesis in animals, an activity believed to result from the transcriptional induction of...

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Bibliografiske detaljer
Main Authors: Cross, Janet V, Foss, Frank W, Rady, Joshua M, Macdonald, Timothy L, Templeton, Dennis J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central|1 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071920/
https://ncbi.nlm.nih.gov/pubmed/17894894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-183
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