Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

The stress-activated protein kinase (SAPK, alternatively JNK) is activated rapidly by cell stress stimuli such as inflammatory cytokines and oxidative stress, and more slowly by the initiation of the apoptotic cell death response by events such as ligation of the Fas protein. Mitogen-activated prote...

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Bibliographic Details
Main Authors: Deak, Joseph C., Cross, Janet V., Lewis, Margaret, Qian, Yongyi, Parrott, Louis A., Distelhorst, Clark W., Templeton, Dennis J.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20423/
https://ncbi.nlm.nih.gov/pubmed/9576928
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