The Novel CXCL12γ Isoform Encodes an Unstructured Cationic Domain Which Regulates Bioactivity and Interaction with Both Glycosaminoglycans and CXCR4

BACKGROUND: CXCL12α, a chemokine that importantly promotes the oriented cell migration and tissue homing of many cell types, regulates key homeostatic functions and pathological processes through interactions with its cognate receptor (CXCR4) and heparan sulfate (HS). The alternative splicing of the...

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Detalhes bibliográficos
Main Authors: Laguri, Cédric, Sadir, Rabia, Rueda, Patricia, Baleux, Françoise, Gans, Pierre, Arenzana-Seisdedos, Fernando, Lortat-Jacob, Hugues
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040504/
https://ncbi.nlm.nih.gov/pubmed/17971873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001110
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