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The Novel CXCL12γ Isoform Encodes an Unstructured Cationic Domain Which Regulates Bioactivity and Interaction with Both Glycosaminoglycans and CXCR4

BACKGROUND: CXCL12α, a chemokine that importantly promotes the oriented cell migration and tissue homing of many cell types, regulates key homeostatic functions and pathological processes through interactions with its cognate receptor (CXCR4) and heparan sulfate (HS). The alternative splicing of the...

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Main Authors: Laguri, Cédric, Sadir, Rabia, Rueda, Patricia, Baleux, Françoise, Gans, Pierre, Arenzana-Seisdedos, Fernando, Lortat-Jacob, Hugues
格式: Artigo
語言:Inglês
出版: Public Library of Science 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040504/
https://ncbi.nlm.nih.gov/pubmed/17971873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001110
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