The CXCL12γ Chemokine Displays Unprecedented Structural and Functional Properties that Make It a Paradigm of Chemoattractant Proteins

The CXCL12γ chemokine arises by alternative splicing from Cxcl12, an essential gene during development. This protein binds CXCR4 and displays an exceptional degree of conservation (99%) in mammals. CXCL12γ is formed by a protein core shared by all CXCL12 isoforms, extended by a highly cationic carbo...

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Detalhes bibliográficos
Main Authors: Rueda, Patricia, Balabanian, Karl, Lagane, Bernard, Staropoli, Isabelle, Chow, Ken, Levoye, Angelique, Laguri, Cedric, Sadir, Rabia, Delaunay, Thierry, Izquierdo, Elena, Pablos, Jose Luis, Lendinez, Elena, Caruz, Antonio, Franco, Diego, Baleux, Françoise, Lortat-Jacob, Hugues, Arenzana-Seisdedos, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481281/
https://ncbi.nlm.nih.gov/pubmed/18648536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002543
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