The Novel CXCL12γ Isoform Encodes an Unstructured Cationic Domain Which Regulates Bioactivity and Interaction with Both Glycosaminoglycans and CXCR4

BACKGROUND: CXCL12α, a chemokine that importantly promotes the oriented cell migration and tissue homing of many cell types, regulates key homeostatic functions and pathological processes through interactions with its cognate receptor (CXCR4) and heparan sulfate (HS). The alternative splicing of the...

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Autors principals: Laguri, Cédric, Sadir, Rabia, Rueda, Patricia, Baleux, Françoise, Gans, Pierre, Arenzana-Seisdedos, Fernando, Lortat-Jacob, Hugues
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040504/
https://ncbi.nlm.nih.gov/pubmed/17971873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001110
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