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NMR characterization of the interaction between the C-terminal domain of interferon-γ and heparin-derived oligosaccharides

Interferons are cytokines that play a complex role in the resistance of mammalian hosts to pathogens. IFNγ (interferon-γ) is secreted by activated T-cells and natural killer cells. IFNγ is involved in a wide range of physiological processes, including antiviral activity, immune response, cell prolif...

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Main Authors: Vanhaverbeke, Cécile, Simorre, Jean-Pierre, Sadir, Rabia, Gans, Pierre, Lortat-Jacob, Hugues
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134092/
https://ncbi.nlm.nih.gov/pubmed/15270718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040757
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