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Molecular organization of the interferon gamma-binding domain in heparan sulphate.

Interferon (IFN)-gamma, in common with a number of cytokines or growth factors, strongly interacts with heparan sulphate (HS). It has been shown previously that one of the C-terminal basic clusters of amino acids (a regulatory element of IFN-gamma activity) is involved in this interaction. The struc...

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Detalhes bibliográficos
Main Authors: Lortat-Jacob, H, Turnbull, J E, Grimaud, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135923/
https://ncbi.nlm.nih.gov/pubmed/7654188
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