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The connection between metal ion affinity and ligand affinity in integrin I domains
Integrins are cell-surface heterodimeric proteins that mediate cell-cell, cell-matrix, and cell-pathogen interactions. Half of the known integrin α subunits contain inserted domains (I domains) that coordinate ligand through a metal ion. Although the importance of conformational changes within isola...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040231/ https://ncbi.nlm.nih.gov/pubmed/17702677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.06.014 |
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