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A Genomic Screen in Yeast Reveals Novel Aspects of Nonstop mRNA Metabolism

Nonstop mRNA decay, a specific mRNA surveillance pathway, rapidly degrades transcripts that lack in-frame stop codons. The cytoplasmic exosome, a complex of 3′–5′ exoribonucleases involved in RNA degradation and processing events, degrades nonstop transcripts. To further understand how nonstop mRNAs...

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Autors principals: Wilson, Marenda A., Meaux, Stacie, van Hoof, Ambro
Format: Artigo
Idioma:Inglês
Publicat: Copyright © 2007 by the Genetics Society of America 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034642/
https://ncbi.nlm.nih.gov/pubmed/17660569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.073205
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