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Genetic interactions between [PSI(+)] and nonstop mRNA decay affect phenotypic variation

Yeast strains can reversibly interconvert between [PSI(+)] and [psi(-)] states. The [PSI(+)] state is caused by a prion form of the translation termination factor eRF3. The [PSI(+)] state causes read-through at stop codons and can lead to phenotypic variation, although the molecular mechanisms causi...

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Detalhes bibliográficos
Main Authors: Wilson, Marenda A., Meaux, Stacie, Parker, Roy, van Hoof, Ambro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173365/
https://ncbi.nlm.nih.gov/pubmed/16002465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504557102
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