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Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail

Eukaryotic mRNAs harboring premature translation termination codons are recognized and rapidly degraded by the nonsense-mediated mRNA decay (NMD) pathway. The mechanism for discriminating between mRNAs that terminate translation prematurely and those subject to termination at natural stop codons rem...

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Detalhes bibliográficos
Main Authors: Meaux, Stacie, van Hoof, Ambro, Baker, Kristian E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241659/
https://ncbi.nlm.nih.gov/pubmed/18206975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.031
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