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Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay

It has been proposed that the 7-methylguanosine cap and poly(A) tail of mRNAs have important functions in translation and transcript stability. To directly test these roles of the cap and poly(A) tail, we have constructed plasmids with a ribozyme within the coding region or 3′ UTR of reporter genes....

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Detalhes bibliográficos
Main Authors: Meaux, Stacie, Van Hoof, Ambro
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484436/
https://ncbi.nlm.nih.gov/pubmed/16714281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.46306
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