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Genetic interactions between [PSI(+)] and nonstop mRNA decay affect phenotypic variation
Yeast strains can reversibly interconvert between [PSI(+)] and [psi(-)] states. The [PSI(+)] state is caused by a prion form of the translation termination factor eRF3. The [PSI(+)] state causes read-through at stop codons and can lead to phenotypic variation, although the molecular mechanisms causi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1173365/ https://ncbi.nlm.nih.gov/pubmed/16002465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504557102 |
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