Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo
Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Δ mutation...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | EMBO J |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2000
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3060 |
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