Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Δ mutation...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	EMBO J
Päätekijät:	Wittschieben, Birgitte Ø., Fellows, Jane, Du, Wendy, Stillman, David J., Svejstrup, Jesper Q.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Publishing Group 2000
Aiheet:	Articles
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3060
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