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Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo
Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Δ mutation...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203375/ https://ncbi.nlm.nih.gov/pubmed/10856249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3060 |
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