Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Δ mutation...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Wittschieben, Birgitte Ø., Fellows, Jane, Du, Wendy, Stillman, David J., Svejstrup, Jesper Q.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2000
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3060
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