Mechanisms of accurate translesion synthesis by human DNA polymerase η
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η (pol η), which is involved in the replication of damaged DNA. Pol η catalyzes efficient and accurate translesion synthesis past cis-syn cyclobutane di-thymine lesions. Here we show that human pol η can catalyze translesion s...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3100 |
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