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Mechanisms of accurate translesion synthesis by human DNA polymerase η
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η (pol η), which is involved in the replication of damaged DNA. Pol η catalyzes efficient and accurate translesion synthesis past cis-syn cyclobutane di-thymine lesions. Here we show that human pol η can catalyze translesion s...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203367/ https://ncbi.nlm.nih.gov/pubmed/10856253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3100 |
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