Molecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patients

Xeroderma pigmentosum variant (XP-V) cells are deficient in their ability to synthesize intact daughter DNA strands after UV irradiation. This deficiency results from mutations in the gene encoding DNA polymerase η, which is required for effecting translesion synthesis (TLS) past UV photoproducts. W...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Broughton, Bernard C., Cordonnier, Agnes, Kleijer, Wim J., Jaspers, Nicolaas G. J., Fawcett, Heather, Raams, Anja, Garritsen, Victor H., Stary, Anne, Avril, Marie-Françoise, Boudsocq, François, Masutani, Chikahide, Hanaoka, Fumio, Fuchs, Robert P., Sarasin, Alain, Lehmann, Alan R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2002
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC117388/
https://ncbi.nlm.nih.gov/pubmed/11773631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022473899
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items