Molecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patients
Xeroderma pigmentosum variant (XP-V) cells are deficient in their ability to synthesize intact daughter DNA strands after UV irradiation. This deficiency results from mutations in the gene encoding DNA polymerase η, which is required for effecting translesion synthesis (TLS) past UV photoproducts. W...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022473899 |
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