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Mechanisms of accurate translesion synthesis by human DNA polymerase η

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η (pol η), which is involved in the replication of damaged DNA. Pol η catalyzes efficient and accurate translesion synthesis past cis-syn cyclobutane di-thymine lesions. Here we show that human pol η can catalyze translesion s...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Masutani, Chikahide, Kusumoto, Rika, Iwai, Shigenori, Hanaoka, Fumio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2000
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.3100
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