Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

Homodimerization of the erythropoietin (EPO) receptor (EPO-R) in response to EPO binding transiently activates the receptor-associated protein tyrosine kinase JAK2. Tyrosine phosphorylation of the EPO-R creates “docking sites” for SH2 domain(s) in signaling molecules such as the protein tyrosine pho...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Klingmüller, Ursula, Wu, Hong, Hsiao, Jonathan G., Toker, Alex, Duckworth, Brian C., Cantley, Lewis C., Lodish, Harvey F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20314/
https://ncbi.nlm.nih.gov/pubmed/9096338
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge