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Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors
Homodimerization of the erythropoietin (EPO) receptor (EPO-R) in response to EPO binding transiently activates the receptor-associated protein tyrosine kinase JAK2. Tyrosine phosphorylation of the EPO-R creates “docking sites” for SH2 domain(s) in signaling molecules such as the protein tyrosine pho...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The National Academy of Sciences of the USA
1997
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20314/ https://ncbi.nlm.nih.gov/pubmed/9096338 |
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