Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

Homodimerization of the erythropoietin (EPO) receptor (EPO-R) in response to EPO binding transiently activates the receptor-associated protein tyrosine kinase JAK2. Tyrosine phosphorylation of the EPO-R creates “docking sites” for SH2 domain(s) in signaling molecules such as the protein tyrosine pho...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Klingmüller, Ursula, Wu, Hong, Hsiao, Jonathan G., Toker, Alex, Duckworth, Brian C., Cantley, Lewis C., Lodish, Harvey F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC20314/
https://ncbi.nlm.nih.gov/pubmed/9096338
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares