BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells

Erythropoietin (Epo)-independent differentiation of erythroid progenitors is a major characteristic of myeloproliferative disorders, including chronic myeloid leukemia. Epo receptor (EpoR) signaling is crucial for normal erythroid development, as evidenced by the properties of Epo(−/−) and EpoR(−/−)...

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Hlavní autoři: Ghaffari, Saghi, Wu, Hong, Gerlach, Melissa, Han, Ying, Lodish, Harvey F., Daley, George Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC23922/
https://ncbi.nlm.nih.gov/pubmed/10557295
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