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Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells

The bcr-abl chimeric oncoprotein exhibits deregulated protein tyrosine kinase activity and is implicated in the pathogenesis of Philadelphia chromosome (Ph)-positive human leukemias, such as chronic myelogenous leukemia (CML). Recently we have shown that the levels of the protein tyrosine phosphatas...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: LaMontagne, Kenneth R., Hannon, Greg, Tonks, Nicholas K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC24332/
https://ncbi.nlm.nih.gov/pubmed/9826659
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