Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

Homodimerization of the erythropoietin (EPO) receptor (EPO-R) in response to EPO binding transiently activates the receptor-associated protein tyrosine kinase JAK2. Tyrosine phosphorylation of the EPO-R creates “docking sites” for SH2 domain(s) in signaling molecules such as the protein tyrosine pho...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Klingmüller, Ursula, Wu, Hong, Hsiao, Jonathan G., Toker, Alex, Duckworth, Brian C., Cantley, Lewis C., Lodish, Harvey F.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1997
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.3016
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!