Pharmacokinetics and pharmacodynamic effects of ABT-627, an oral ETA selective endothelin antagonist, in humans

AIMS: Endothelins (ETs) may play a role in the pathogenesis of a variety of cardiovascular diseases. The present study was designed to investigate the pharmacokinetic and pharmacodynamic effects of the orally active ETA selective receptor antagonist ABT-627 in healthy humans. METHODS: Healthy volunt...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Verhaar, Marianne C, Grahn, Amy Y, van Weerdt, Anton W M, Honing, Marina L H, Morrison, Paul J, Yang, Yonghong P, Padley, Robert J, Rabelink, Ton J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2000
Témata:
Pharmacokinetics/Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015037/
https://ncbi.nlm.nih.gov/pubmed/10848720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00171.x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky