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Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine
AIMS: The aims of the present study were to investigate the metabolism of astemizole in human liver microsomes, to assess possible pharmacokinetic drug-interactions with astemizole and to compare its metabolism with terfenadine, a typical H(1) receptor antagonist known to be metabolized predominantl...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014443/ https://ncbi.nlm.nih.gov/pubmed/11259984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2001.01292.x |
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