Metabolic capabilities of cytochrome P450 enzymes in Chinese liver microsomes compared with those in Caucasian liver microsomes

AIM: The most common causes of variability in drug response include differences in drug metabolism, especially when the hepatic cytochrome P450 (CYP) enzymes are involved. The current study was conducted to assess the differences in CYP activities in human liver microsomes (HLM) of Chinese or Caucas...

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Detalhes bibliográficos
Main Authors: Yang, Junling, He, Minxia M, Niu, Wei, Wrighton, Steven A, Li, Li, Liu, Yang, Li, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Drug Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269586/
https://ncbi.nlm.nih.gov/pubmed/21815912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04076.x
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