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A model for size and age changes in the pharmacokinetics of paracetamol in neonates, infants and children

AIMS: The aims of this study were to describe paracetamol pharmacokinetics in neonates and infants. METHODS: Infants in their first 3 months of life (n = 30) were randomised to sequentially receive one of three paracetamol formulations (dose 30–40 mg kg(−1)) over a 2 day period. The formulations wer...

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Main Authors: Anderson, Brian J, Woollard, Gerald A, Holford, Nicholas H G
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014402/
https://ncbi.nlm.nih.gov/pubmed/10930964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00231.x
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